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3-phenylpyrazolo[1,5-a]pyrimidine synthesis

2synthesis methods
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Yield:72851-18-4 23 %Spectr. ,394208-27-6 7 %Spectr.

Reaction Conditions:

with palladium diacetate;caesium carbonate;4,5-bis(diphenylphosphino)-9,9-dimethylxanthene in 1-methyl-pyrrolidin-2-one at 150; for 18 h;regioselective reaction;

References:

Bedford, Robin B.;Durrant, Steven J.;Montgomery, Michelle [Angewandte Chemie - International Edition,2015,vol. 54,# 30,p. 8787 - 8790][Angew. Chem.,2015,vol. 54,# 30,p. 8911 - 8914,4] Location in patent:supporting information

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