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3-(pyrrolidin-1-ylmethyl)benzoic acid synthesis

3synthesis methods
-

Yield:884507-41-9 34%

Reaction Conditions:

with sodium tris(acetoxy)borohydride;acetic acid in 1,2-dichloro-ethane at 20; for 24 h;

References:

Keurulainen, Leena;Vahermo, Mikko;Puente-Felipe, Margarita;Sandoval-Izquierdo, Elena;Crespo-Fernández, Benigno;Guijarro-López, Laura;Huertas-Valentín, Leticia;De Las Heras-Due?a, Laura;Leino, Teppo O.;Siiskonen, Antti;Ballell-Pages, Lluís;Sanz, Laura M.;Casta?eda-Casado, Pablo;Jiménez-Díaz, M. Belén;Martínez-Martínez, María S.;Viera, Sara;Kiuru, Paula;Calderón, Félix;Yli-Kauhaluoma, Jari [Journal of Medicinal Chemistry,2015,vol. 58,# 11,p. 4573 - 4580] Location in patent:supporting information

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