3-Quinolinecarboxylicacid,7-fluoro-4-hydroxy-(9CI) synthesis
- Product Name:3-Quinolinecarboxylicacid,7-fluoro-4-hydroxy-(9CI)
- CAS Number:63463-20-7
- Molecular formula:C10H6FNO3
- Molecular Weight:207.16
26892-97-7
20 suppliers
inquiry
63463-20-7
19 suppliers
inquiry
Yield:-
Reaction Conditions:
in sodium hydroxide;
Steps:
48.B Part B
Part B A suspension of ethyl 7-fluoro-4-hydroxy-3-quinolinecarboxylate (65 g, 0.28 mol) in 10% sodium hydroxide (250 mL) was heated at reflux for 3 hours during which time a solution was obtained. The reaction mixture was allowed to cool to ambient temperature and then it was filtered through filter paper under vacuum. The filtrate was acidified with concentrated hydrochloric acid. The resulting precipitate was collected, washed with water and then dried to provide 53.5 g of 7-fluoro-4-hydroxy-3-quinolinecarboxylic acid as a white solid.
References:
US6110929,2000,A
372-19-0
321 suppliers
$10.00/1g
63463-20-7
19 suppliers
inquiry
![diethyl {[(3-fluorophenyl)amino]methylidene}propanedioate](/CAS/20180703/GIF/26832-95-1.gif)
26832-95-1
6 suppliers
inquiry
63463-20-7
19 suppliers
inquiry