![](/CAS/20150408/GIF/219508-27-7.gif)
3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole synthesis
- Product Name:3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole
- CAS Number:219508-27-7
- Molecular formula:C8H5F3N4
- Molecular Weight:214.15
![2-Cyanopyridine](/CAS/GIF/100-70-9.gif)
100-70-9
403 suppliers
$13.00/25g
![TRIFLUOROACETIC ACID HYDRAZIDE](/CAS/GIF/1538-08-5.gif)
1538-08-5
119 suppliers
$5.00/100mg
![3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole](/CAS/20150408/GIF/219508-27-7.gif)
219508-27-7
37 suppliers
$60.00/5mg
Yield:219508-27-7 52%
Reaction Conditions:
Stage #1: 2-Cyanopyridine;2,2,2-trifluoroacetohydrazide in ethanol at 20; for 0.5 h;
Stage #2: with sodium methylate in methanol;ethanol at 130; for 14 h;Reflux;
References:
Park, Hea Jung;Kim, Ji Na;Yoo, Hyun-Ji;Wee, Kyung-Ryang;Kang, Sang Ook;Cho, Dae Won;Yoon, Ung Chan [Journal of Organic Chemistry,2013,vol. 78,# 16,p. 8054 - 8064]
![2-Cyanopyridine](/CAS/GIF/100-70-9.gif)
100-70-9
403 suppliers
$13.00/25g
![3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole](/CAS/20150408/GIF/219508-27-7.gif)
219508-27-7
37 suppliers
$60.00/5mg
![pyridine-2-carboximidohydrazide](/CAS/GIF/1005-02-3.gif)
1005-02-3
46 suppliers
$89.00/1g
![3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole](/CAS/20150408/GIF/219508-27-7.gif)
219508-27-7
37 suppliers
$60.00/5mg
![METHYL PICOLINIMIDATE](/CAS/GIF/19547-38-7.gif)
19547-38-7
73 suppliers
$120.00/5g
![3-(Trifluoromethyl)-5-(2-pyridyl)-1,2,4-triazole](/CAS/20150408/GIF/219508-27-7.gif)
219508-27-7
37 suppliers
$60.00/5mg