3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE synthesis
- Product Name:3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE
- CAS Number:38923-38-5
- Molecular formula:C9H5F3O2
- Molecular Weight:202.13
349-76-8
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$10.00/1g
38923-38-5
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$225.00/250mg
Yield:38923-38-5 100%
Reaction Conditions:
with water;hydrogen bromide;dimethyl sulfoxide at 20 - 70;
Steps:
8 REFERENCE SYNTHETIC EXAMPLE 8; Synthesis of (3-trifluoromethylphenyl)(oxo)acetaldehyde
3-Trifluoromethylacetophenone (11.80 mmol, 2.22 g) was dissolved in dimethyl sulfoxide (13 mL), and 48% hydrobromic acid (5.4 mL) was gradually added at roomtemperature. After overnight stirring at 70°C, the reactor was cooled to room temperature. After addition of water, the reaction solution was extracted with chloroform, and the extract was dried and filtered, and the solvent was evaporated to give the desired product as a yellow liquid (3.04 g (crude), yield 128%)
References:
WO2004/108683,2004,A1 Location in patent:Page 535
2003-10-3
109 suppliers
$16.00/250mg
38923-38-5
16 suppliers
$225.00/250mg