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3-(triMethylsilyl)phenol synthesis

4synthesis methods
-

Yield:17881-95-7 90%

Reaction Conditions:

Stage #1: 3-Bromophenolwith n-butyllithium in tetrahydrofuran;hexane at -78;
Stage #2: chloro-trimethyl-silane in tetrahydrofuran;hexane;

References:

Nishide, Kiyoharu;Ohsugi, Shin-Ichi;Miyamoto, Tetsuo;Kumar, Kamal;Node, Manabu [Monatshefte fur Chemie,2004,vol. 135,# 2,p. 189 - 200]