ChemicalBook CAS DataBase List 5-(4-FLUORO-PHENYL)-7-TRIFLUOROMETHYL-PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID

5-(4-FLUORO-PHENYL)-7-TRIFLUOROMETHYL-PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID synthesis

2synthesis methods

Product Name:5-(4-FLUORO-PHENYL)-7-TRIFLUOROMETHYL-PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID
CAS Number:310451-82-2
Molecular formula:C14H7F4N3O2
Molecular Weight:325.22

Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5-(4-fluorophenyl)-7-(trifluoromethyl)-, ethyl ester

333761-06-1
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5-(4-FLUORO-PHENYL)-7-TRIFLUOROMETHYL-PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID

310451-82-2
17 suppliers
$189.00/500mg

Yield:310451-82-2 65%

Reaction Conditions:

Stage #1: C₁₆H₁₁F₄N₃O₂with sodium hydroxide in ethanol;water at 65; for 4 h;
Stage #2: with hydrogenchloride at 20; pH=1;

References:

Mulakayala, Naveen;Reddy, Upendar;Chaitanya;Hussain, Manzoor;Kumar, Chitta Suresh;Golla, Narayanaswamy [Journal of the Korean Chemical Society,2011,vol. 55,# 4,p. 719 - 722] Location in patent:experimental part

4,4,4-TRIFLUORO-1-(4-FLUOROPHENYL)BUTANE-1,3-DIONE

582-65-0
69 suppliers
$33.39/1g

310451-82-2
17 suppliers
$189.00/500mg

References