N-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-4-methylbenzenesulfonamide synthesis
1synthesis methods
- Product Name:N-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-4-methylbenzenesulfonamide
- CAS Number:313952-75-9
- Molecular formula:C10H12N4O2S2
- Molecular Weight:284.36
Yield:313952-75-9 54%
Reaction Conditions:
Stage #1: thiosemicarbazidewith 1-ethyl-3-methylimidazolium hydrogensulfate at 20; for 0.25 h;
Stage #2: N-Tosylglycinewith sulfuric acid at 100;
References:
Epishina, Margarita A.;Kulikov, Alexander S.;Ignat'Ev, Nikolai V.;Schulte, Michael;Makhova, Nina N. [Mendeleev Communications,2011,vol. 21,# 6,p. 331 - 333] Location in patent:experimental part