5-BROMO-3-METHYLBENZO[B]THIOPHENE-2-SULPHONYL CHLORIDE synthesis

3synthesis methods

Product Name:5-BROMO-3-METHYLBENZO[B]THIOPHENE-2-SULPHONYL CHLORIDE
CAS Number:338797-11-8
Molecular formula:C9H6BrClO2S2
Molecular Weight:325.63

1196-09-4
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5-BROMO-3-METHYLBENZO[B]THIOPHENE-2-SULPHONYL CHLORIDE

338797-11-8
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$44.00/250mg

Yield:338797-11-8 39%

Reaction Conditions:

with chlorosulfonic acid in chloroform at -5 - 0;

Steps:

Chlorosulfonic acid (2.20 ml, 0.033 mmol) was added dropwise at -5 °C to a solution of 5- bromo-3-methylbenzothiophene (Intermediate 9) (3.0 g, 13.2 mmol) in CHCI3 (30 mL). The reaction mixture was stirred at 0 °C for 3 h, and then poured into a mixture of ice/NaHC0₃ and stirred vigorously for 5 min. The organic phase was immediately separated, dried and concentrated to give the title compound (1.70 g, 39%).

References:

WO2012/35171,2012,A2 Location in patent:Page/Page column 50

106-53-6 Synthesis

106-53-6
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338797-11-8
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$44.00/250mg

References

1200-12-0
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338797-11-8
16 suppliers
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References