ChemicalBook CAS DataBase List 1-ALLYL-2-[(4-FLUOROBENZYL)SULFONYL]-4,5-DIPHENYL-1H-IMIDAZOLE

1-ALLYL-2-[(4-FLUOROBENZYL)SULFONYL]-4,5-DIPHENYL-1H-IMIDAZOLE synthesis

4synthesis methods

Product Name:1-ALLYL-2-[(4-FLUOROBENZYL)SULFONYL]-4,5-DIPHENYL-1H-IMIDAZOLE
CAS Number:339277-78-0
Molecular formula:C25H21FN2O2S
Molecular Weight:432.51

1H-Imidazole, 2-[[(4-fluorophenyl)methyl]sulfonyl]-4,5-diphenyl-

1443114-23-5
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106-95-6 Synthesis

106-95-6
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1-ALLYL-2-[(4-FLUOROBENZYL)SULFONYL]-4,5-DIPHENYL-1H-IMIDAZOLE

339277-78-0
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Yield:339277-78-0 70 mg

Reaction Conditions:

Stage #1: 2-(4-fluorobenzylsulfonyl)-4,5-diphenyl-1H-imidazolewith caesium carbonate in N,N-dimethyl-formamide at 20; for 0.0833333 h;Inert atmosphere;
Stage #2: allyl bromide in N,N-dimethyl-formamide at 20; for 20 h;Inert atmosphere;

References:

Moore, Terry W.;Sana, Kasinath;Yan, Dan;Krumm, Stefanie A.;Thepchatri, Pahk;Snyder, James P.;Marengo, Jose;Arrendale, Richard F.;Prussia, Andrew J.;Natchus, Michael G.;Liotta, Dennis C.;Plemper, Richard K.;Sun, Aiming [ACS Medicinal Chemistry Letters,2013,vol. 4,# 8,p. 762 - 767] Location in patent:supporting information

2349-58-8
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339277-78-0
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References

459-46-1
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339277-78-0
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References

2-[(4-FLUOROBENZYL)SULFANYL]-4,5-DIPHENYL-1H-IMIDAZOLE

339277-38-2
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339277-78-0
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References