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ChemicalBook CAS DataBase List 1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea

1-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)-1,3-dimethylurea synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: hydrazine hydrate; aluminum oxide / toluene / Reflux
2: toluene / 2 h / Reflux
3: sulfuric acid; toluene-4-sulfonic acid / 75 - 85 °C
4: triethylamine / toluene / 0 °C
5: tetrahydrofuran / Reflux

References:

Jiangsu Kuai Da Agrochemical Co., Ltd.;Li Wei;Qian Shengli;Han Bangyou;Xu Xuefei;Huang Zhihong;Lin Longlong;Wu Chongzheng;Wu Chunhui CN108794427, 2018, A

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