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ChemicalBook CAS DataBase List 1α-(4-Hydroxybenzyl)-2-methyl-1,2,3,4-tetrahydro-6-methoxyisoquinoline-7-ol
3423-07-2

1α-(4-Hydroxybenzyl)-2-methyl-1,2,3,4-tetrahydro-6-methoxyisoquinoline-7-ol synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 5 steps
1: 15 mg / Zn; aq. AcOH / 2 h
2: 11 mg / HCl / methanol; H2O / 2 h / Heating
3: 4.5 mg / HCO2H / methanol / 1 h / Heating
4: 85 mg / methanol / 120 h
5: 10 mg / Na / liquid ammonia; tetrahydrofuran / -50 - -30 °C

References:

Lee, Shoei-Sheng;Wu, Wu-Nan;Wilton, John H.;Beal, Jack L.;Doskotch, Raymond W. [Journal of Natural Products,1999,vol. 62,# 10,p. 1410 - 1414]