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347319-95-3

2-(3-FORMYL-INDOL-1-YL)-N-FURAN-2-YLMETHYL-ACETAMIDE synthesis

1synthesis methods
-

Yield:347319-95-3 83%

Reaction Conditions:

Stage #1: Indole-3-carboxaldehydewith sodium hydride in N,N-dimethyl-formamide; for 1 h;
Stage #2: 2-chloro-N-furfurylacetamide in N,N-dimethyl-formamide;Further stages.;

References:

Hartzoulakis, Basil;Rossiter, Sharon;Gill, Herpreet;O'Hara, Bernard;Steinke, Emily;Gane, Paul J.;Hurtado-Guerrero, Ramon;Leiper, James M.;Vallance, Patrick;Rust, Judith Murray;Selwood, David L. [Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,# 14,p. 3953 - 3956]