ChemicalBook CAS DataBase List METHYL 2-(TRIFLUOROMETHYL)-3,3,3-TRIFLUOROPROPIONATE

METHYL 2-(TRIFLUOROMETHYL)-3,3,3-TRIFLUOROPROPIONATE synthesis

7synthesis methods

Product Name:METHYL 2-(TRIFLUOROMETHYL)-3,3,3-TRIFLUOROPROPIONATE
CAS Number:360-54-3
Molecular formula:C5H4F6O2
Molecular Weight:210.07

1-METHOXY-(PERFLUORO-2-METHYL-1-PROPENE)

360-53-2
36 suppliers
$65.00/1 g

METHYL 2-(TRIFLUOROMETHYL)-3,3,3-TRIFLUOROPROPIONATE

360-54-3
55 suppliers
$45.00/50mg

Yield:-

Reaction Conditions:

with lithium chloride in tetrahydrofuran;methanol at 70; for 4 h;Reagent/catalyst;Temperature;

Steps:

1
In a 250ml three-necked round bottom flask,106g(0.5mol) sevofluoro isobutylene methyl ether and absolute methanol, solvent tetrahydrofuran (THF) 120ml, halide were added seperately, after the addition is complete, slowly raise the temperature to the reaction temperature to start the reaction with stirring, After the reaction was cooled and filtered, the filtrate was distilled at atmospheric pressure to give hexafluoro methyl isobutyrate

References:

Juhua Group Technology Center;Lv Yang;Ye Lifeng;Jiang Qi;Li Hongfeng;Wang Zongling CN107151198, 2017, A Location in patent:Paragraph 0039; 0045-0049