ChemicalBook CAS DataBase List 2-CHLORO-N-(2-TRIFLUOROMETHYL-1H-BENZOIMIDAZOL-5-YL)-ACETAMIDE

2-CHLORO-N-(2-TRIFLUOROMETHYL-1H-BENZOIMIDAZOL-5-YL)-ACETAMIDE synthesis

1synthesis methods

Product Name:2-CHLORO-N-(2-TRIFLUOROMETHYL-1H-BENZOIMIDAZOL-5-YL)-ACETAMIDE
CAS Number:362594-28-3
Molecular formula:C10H7ClF3N3O
Molecular Weight:277.63

79-04-9 Synthesis

79-04-9
350 suppliers
$12.00/5g

5-AMINO-2-(TRIFLUOROMETHYL)BENZIMIDAZOLE

3671-66-7
79 suppliers
$31.00/1g

2-CHLORO-N-(2-TRIFLUOROMETHYL-1H-BENZOIMIDAZOL-5-YL)-ACETAMIDE

362594-28-3
10 suppliers
$253.00/100mg

Yield:362594-28-3 64%

Reaction Conditions:

in N,N-dimethyl acetamide at 0 - 20;

References:

Flipo, Marion;Willand, Nicolas;Lecat-Guillet, Nathalie;Hounsou, Candide;Desroses, Matthieu;Leroux, Florence;Lens, Zoé;Villeret, Vincent;Wohlk?nig, Alexandre;Wintjens, René;Christophe, Thierry;Kyoung Jeon, Hee;Locht, Camille;Brodin, Priscille;Baulard, Alain R;Déprez, Benoit [Journal of Medicinal Chemistry,2012,vol. 55,# 14,p. 6391 - 6402] Location in patent:supporting information; experimental part