(R)-2-Amino-3-(benzo[d][1,3]dioxol-5-yl)propanoic acid synthesis

10synthesis methods

Product Name:(R)-2-Amino-3-(benzo[d][1,3]dioxol-5-yl)propanoic acid
CAS Number:37002-51-0
Molecular formula:C10H11NO4
Molecular Weight:209.2

1,3-Benzodioxole-5-propanoic acid, α-oxo-

884-18-4
2 suppliers
inquiry

(R)-2-Amino-3-(benzo[d][1,3]dioxol-5-yl)propanoic acid

37002-51-0
2 suppliers
inquiry

Yield:96 % ee

Reaction Conditions:

with D-glucose;pyridoxal 5'-phosphate;D-amino acid aminotransferase from Bacillus sp mutant T₂₄₂G in aq. phosphate buffer;dimethyl sulfoxide at 37; pH=8; for 12 h;Enzymatic reaction;enantioselective reaction;

References:

Walton, Curtis J. W.;Parmeggiani, Fabio;Barber, Janet E. B.;McCann, Jenna L.;Turner, Nicholas J.;Chica, Roberto A. [ChemCatChem,2018,vol. 10,# 2,p. 470 - 474]

2606-51-1 Synthesis