Ethyl2-chloro-2-[2-(2-nitrophenyl)hydrazono]acetate synthesis
4synthesis methods
- Product Name:Ethyl2-chloro-2-[2-(2-nitrophenyl)hydrazono]acetate
- CAS Number:37522-26-2
- Molecular formula:C10H10ClN3O4
- Molecular Weight:271.66
Yield:37522-26-2 73%
Reaction Conditions:
Stage #1: 2-nitro-anilinewith hydrogenchloride;sodium nitrite in methanol;water; for 0.25 h;Cooling with ice;
Stage #2: ethyl 2-chloro-3-oxo-butyrate in methanol;water at 0 - 20; for 1.5 h;
References:
Bodzioch, Agnieszka;Pomik?o, Dominika;Celeda, Ma?gorzata;Pietrzak, Anna;Kaszyński, Piotr [Journal of Organic Chemistry,2019,vol. 84,# 10,p. 6377 - 6394]
