(1S)-3-[3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]oct-8-yl]-1-phenyl-1-propanamine synthesis

12synthesis methods

Product Name:(1S)-3-[3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]oct-8-yl]-1-phenyl-1-propanamine
CAS Number:376348-71-9
Molecular formula:C22H33N5
Molecular Weight:367.53

376348-70-8 Synthesis

((S)-3-[3-(3-ISOPROPYL-5-METHYL-[1,2,4]TRIAZOL-4-YL)-8-AZA-BICYCLO[3.2.1]OCT-8-YL]-1-PHENYL-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER

376348-70-8
8 suppliers
inquiry

(1S)-3-[3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-exo-8-azabicyclo[3.2.1]oct-8-yl]-1-phenyl-1-propanamine

376348-71-9
21 suppliers
$135.00/5MG

Yield:376348-71-9 100%

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane;methanol;water at 20; for 3 h;

References:

Li, Dongmei;Tan, Yu;Peng, Lei;Li, Shan;Zhang, Nan;Liu, Yidong;Yan, Hailong [Organic Letters,2018,vol. 20,# 16,p. 4959 - 4963] Location in patent:supporting information

376348-80-0
2 suppliers
inquiry

376348-71-9
21 suppliers
$135.00/5MG

References

(S)-tert-butyl 3-oxo-1-phenylpropylcarbamate

135865-78-0
93 suppliers
$64.00/100mg

376348-71-9
21 suppliers
$135.00/5MG

References

190189-97-0 Synthesis

Methyl (3S)-3-Boc-amino-3-phenylpropionate

190189-97-0
26 suppliers
$400.00/1g

376348-71-9
21 suppliers
$135.00/5MG

References

28957-72-4 Synthesis

28957-72-4
208 suppliers
$30.00/1g

376348-71-9
21 suppliers
$135.00/5MG

References