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3-(4-CHLORO-2-FLUORO-PHENYL)-PROPIONIC ACID ETHYL ESTER synthesis

3synthesis methods
2-Propenoic acid, 3-(4-chloro-2-fluorophenyl)-, ethyl ester, (2E)-

500102-63-6
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3-(4-CHLORO-2-FLUORO-PHENYL)-PROPIONIC ACID ETHYL ESTER

377083-98-2
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Yield:377083-98-2 38.3 g

Reaction Conditions:

with hydrogen;platinum(IV) oxide in ethanol;

References:

Musso, David L.;Orr, G. Faye;Cochran, Felicia R.;Kelley, James L.;Selph, Jeffrey L.;Rigdon, Greg C.;Cooper, Barrett R.;Jones, Michael L. [Journal of Medicinal Chemistry,2003,vol. 46,# 3,p. 409 - 416]