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ChemicalBook CAS DataBase List 7-Fluoro-N-(5-chloro-1,3-benzodioxol-4-yl)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine

7-Fluoro-N-(5-chloro-1,3-benzodioxol-4-yl)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine synthesis

7synthesis methods
791602-75-0 Synthesis
4-Chloro-5,7-difluoroquinazoline

791602-75-0
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 3 h / 44 °C / Large scale reaction
2: sodium tert-pentoxide / 1-methyl-pyrrolidin-2-one / 5 h / 55 °C / Large scale reaction

References:

Raw, Steven A.;Taylor, Brian A.;Tomasi, Simone [Organic process research and development,2011,vol. 15,# 3,p. 688 - 692]