(5,6-DIMETHYL-THIENO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC ACID synthesis

1synthesis methods

Product Name:(5,6-DIMETHYL-THIENO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC ACID
CAS Number:384353-04-2
Molecular formula:C10H11N3O2S
Molecular Weight:237.28

56-40-6 Synthesis

56-40-6
1205 suppliers
$5.00/25g

4-CHLORO-5,6-DIMETHYLTHIENO[2,3-D]PYRIMIDINE

108831-68-1
91 suppliers
$38.20/250mg

(5,6-DIMETHYL-THIENO[2,3-D]PYRIMIDIN-4-YLAMINO)-ACETIC ACID

384353-04-2
13 suppliers
$307.00/1g

Yield:384353-04-2 81%

Reaction Conditions:

Stage #1: glycinewith sodium carbonate in water; pH=9 - 9.5;
Stage #2: 4-chloro-5,6-dimethyl-thieno[2,3-d]pyrimidine in water at 100; pH=9 - 9.5; for 6 h;

References:

Alqasoumi, Saleh I.;Ragab, Fatma A.;Alafeefy, Ahmed M.;Galal, Marwa;Ghorab, Mostafa M. [Phosphorus, Sulfur and Silicon and the Related Elements,2009,vol. 184,# 12,p. 3241 - 3257] Location in patent:experimental part