ETHYL 4-ACETYL-5-ANILINO-3-METHYL-2-THIOPHENECARBOXYLATE synthesis
- Product Name:ETHYL 4-ACETYL-5-ANILINO-3-METHYL-2-THIOPHENECARBOXYLATE
- CAS Number:393802-93-2
- Molecular formula:C16H17NO3S
- Molecular Weight:303.38
103-72-0
228 suppliers
$10.00/1g
105-36-2
344 suppliers
$5.00/5G
123-54-6
565 suppliers
$10.00/25ml
393802-93-2
10 suppliers
$115.00/1g
Yield:393802-93-2 47%
Reaction Conditions:
Stage #1: acetylacetonewith potassium carbonate in N,N-dimethyl-formamide at 20; for 1 h;
Stage #2: phenyl isothiocyanate in N,N-dimethyl-formamide at 20; for 2 h;
Stage #3: ethyl bromoacetatewith potassium carbonate in N,N-dimethyl-formamide at 20; for 4 h;Dieckmann type cyclisation;
References:
Sommen;Comel;Kirsch [Synlett,2001,# 11,p. 1731 - 1734]