ChemicalBook CAS DataBase List 5N-BOC-3-AMINO-4,6-DIHYDRO-1H-PYRROLO[3,4-C]PYROZOLE

5N-BOC-3-AMINO-4,6-DIHYDRO-1H-PYRROLO[3,4-C]PYROZOLE synthesis

6synthesis methods

Product Name:5N-BOC-3-AMINO-4,6-DIHYDRO-1H-PYRROLO[3,4-C]PYROZOLE
CAS Number:398491-59-3
Molecular formula:C10H16N4O2
Molecular Weight:224.26

175463-32-8 Synthesis

175463-32-8
249 suppliers
$6.00/1g

5N-BOC-3-AMINO-4,6-DIHYDRO-1H-PYRROLO[3,4-C]PYROZOLE

398491-59-3
165 suppliers
$45.00/10mg

Yield: 66%

Reaction Conditions:

with hydrazine in ethanol at 60; for 3 h;

Steps:

1.1 Step 1: Preparation of intermediate 1b
(4.5 g, 43 mmol) was dissolved in absolute ethanol (250 ml) and stirred at 60 ° C for 3 h. The solvent was distilled off under reduced pressure and saturated sodium bicarbonate solution (50 ml) was added to a solid completely dissolved,The extracted organic phase was removed by evaporation under reduced pressure to give the white solid Ib (6.3 g, yield 66%) which was used in the next step without further purification.

References:

Beijing Ruichuang Zhiyuan Biological Technology Co., Ltd.;Qiao Dehua CN106279177, 2017, A Location in patent:Paragraph 0103; 0104; 0105