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ChemicalBook CAS DataBase List (3S)-1-benzyl-5-oxopyrrolidine-3-carboxylic acid
428518-42-7

(3S)-1-benzyl-5-oxopyrrolidine-3-carboxylic acid synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 85 percent / methanol / 12 h / 20 °C
2: 28 percent / α-chymotrypsine (α-CT) / aq. phosphate buffer / 20 °C / pH 7.4 / low conversion

References:

Felluga, Fulvia;Pitacco, Giuliana;Prodan, Massimo;Pricl, Sabrina;Visintin, Marco;Valentin, Ennio [Tetrahedron Asymmetry,2001,vol. 12,# 23,p. 3241 - 3249]