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ChemicalBook CAS DataBase List 4-[1,2,3]TRIAZOL-1-YL-BENZALDEHYDE
41498-10-6

4-[1,2,3]TRIAZOL-1-YL-BENZALDEHYDE synthesis

5synthesis methods
-

Yield:41498-10-6 92%

Reaction Conditions:

Stage #1: 4-formylphenylboronic acid,with copper(l) iodide;sodium azide in water;N,N-dimethyl-formamide at 80; for 0.5 h;
Stage #2: Propiolic acidwith 1,8-diazabicyclo[5.4.0]undec-7-ene;sodium L-ascorbate in water;N,N-dimethyl-formamide at 80; for 2.5 h;

References:

Yang, Qing;Jiang, Yubo;Kuang, Chunxiang [Helvetica Chimica Acta,2012,vol. 95,# 3,p. 448 - 454] Location in patent:experimental part

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