4(1H)-Pyrimidinone, 5-(4-chlorophenyl)-6-hydroxy- synthesis
- Product Name:4(1H)-Pyrimidinone, 5-(4-chlorophenyl)-6-hydroxy-
- CAS Number:3979-80-4
- Molecular formula:C10H7ClN2O2
- Molecular Weight:222.63
Yield:3979-80-4 81%
Reaction Conditions:
with sodium methylate in methanol at 60;
References:
Matulenko, Mark A.;Paight, Ernest S.;Frey, Robin R.;Gomtsyan, Arthur;DiDomenico Jr., Stanley;Jiang, Meiqun;Lee, Chih-Hung;Stewart, Andrew O.;Yu, Haixia;Kohlhaas, Kathy L.;Alexander, Karen M.;McGaraughty, Steve;Mikusa, Joseph;Marsh, Kennan C.;Muchmore, Steven W.;Jakob, Clarissa L.;Kowaluk, Elizabeth A.;Jarvis, Michael F.;Bhagwat, Shripad S. [Bioorganic and Medicinal Chemistry,2007,vol. 15,# 4,p. 1586 - 1605]
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