ChemicalBook CAS DataBase List 4-(2,4-DIFLUOROPHENOXY)PIPERIDINE HYDROCHLORIDE

4-(2,4-DIFLUOROPHENOXY)PIPERIDINE HYDROCHLORIDE synthesis

3synthesis methods

Product Name:4-(2,4-DIFLUOROPHENOXY)PIPERIDINE HYDROCHLORIDE
CAS Number:1171775-66-8
Molecular formula:C11H14ClF2NO
Molecular Weight:249.6848

1-Piperidinecarboxylic acid, 4-(2,4-difluorophenoxy)-, 1,1-dimethylethyl ester

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4-(2,4-DIFLUOROPHENOXY)PIPERIDINE HYDROCHLORIDE

1171775-66-8
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$240.00/100mg

Yield:-

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane at 20;Inert atmosphere;

Steps:

23.2

A 4N-hydrochloric acid 1,4-dioxane solution (30 ml) was added to a 1,4-dioxane solution (30 ml) of t-butyl 4-(2,4-difluorophenoxy)piperidine-1-carboxylate (2.28 g, 7.28 mmol), under nitrogen stream, and the mixture was allowed to react at room temperature overnight. The reaction solution was concentrated to afford 4-(2,4-difluorophenoxy)piperidine hydrochloride (1.63 g) as a white solid.

References:

EP2258697,2010,A1 Location in patent:Page/Page column 43

109384-19-2 Synthesis

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1171775-66-8
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$240.00/100mg

References

367-27-1 Synthesis

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1171775-66-8
25 suppliers
$240.00/100mg

References