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4-(2-aminoethyl)-1-hydroxy-2-sulfooxy-benzene synthesis

13synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 13 percent / NaHCO3 / ethanol / 16 h / Heating
2: 1.) NaH, 2.) Me3N*SO3 / DMF, 1.) 30 min, room temp., 2.) 30 min
3: H2 / 10 percent Pd/C / ethanol / 0.5 h / 2280.2 - 3037.7 Torr

References:

Casagrande;Santangelo;Saini;Doggi;Gerli;Cerri [Arzneimittel-Forschung/Drug Research,1986,vol. 36,# 2 A,p. 291 - 303]