4-(2-CHLOROPHENYL)-3-THIOSEMICARBAZIDE synthesis
- Product Name:4-(2-CHLOROPHENYL)-3-THIOSEMICARBAZIDE
- CAS Number:42135-75-1
- Molecular formula:C7H8ClN3S
- Molecular Weight:201.68
2740-81-0
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42135-75-1
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Yield:42135-75-1 89%
Reaction Conditions:
with hydrazine hydrate in isopropyl alcohol at 20; for 3 h;Inert atmosphere;
Steps:
4.2. General procedure for the synthesis of thiosemicarbazidederivatives (1-30)
General procedure: To a stirred solution of hydrazine hydrate (85%, 2.4 mmol) in 20 mL of isopropanol, appropriately substituted isothiocyanate(2.0 mmol) was added at room temperature. Precipitate was formed immediately. Stirring was continued for 3 h. Then the mixture was filtered and the precipitate was washed with isopropanol three times to give the desired product.
References:
Serra, Silvia;Moineaux, Laurence;Vancraeynest, Christelle;Masereel, Bernard;Wouters, Johan;Pochet, Lionel;Frédérick, Rapha?l [European Journal of Medicinal Chemistry,2014,vol. 82,p. 96 - 105]
95-51-2
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42135-75-1
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![[(2-chlorophenyl)amino]methanedithioic acid](/CAS/20180601/GIF/66065-30-3.gif)
66065-30-3
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42135-75-1
38 suppliers
$21.00/1g