ChemicalBook CAS DataBase List 4-(2-Chloropyridin-3-yl)pyrimidin-2-amine

4-(2-Chloropyridin-3-yl)pyrimidin-2-amine synthesis

2synthesis methods

Product Name:4-(2-Chloropyridin-3-yl)pyrimidin-2-amine
CAS Number:870221-49-1
Molecular formula:C9H7ClN4
Molecular Weight:206.63

2-Propen-1-one, 1-(2-chloro-3-pyridinyl)-3-(dimethylamino)-, (2E)-

870221-50-4
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4-(2-Chloropyridin-3-yl)pyrimidin-2-amine

870221-49-1
16 suppliers
$140.00/250mg

Yield:870221-49-1 85%

Reaction Conditions:

with guanidine hydrochloride;sodium methylate in methanol at 50;Inert atmosphere;

References:

Geuns-Meyer, Stephanie;Cee, Victor J.;Deak, Holly L.;Du, Bingfan;Hodous, Brian L.;Nguyen, Hanh Nho;Olivieri, Philip R.;Schenkel, Laurie B.;Vaida, Karina R.;Andrews, Paul;Bak, Annette;Be, Xuhai;Beltran, Pedro J.;Bush, Tammy L.;Chaves, Mary K.;Chung, Grace;Dai, Yang;Eden, Patrick;Hanestad, Kelly;Huang, Liyue;Lin, Min-Hwa Jasmine;Tang, Jin;Ziegler, Beth;Radinsky, Robert;Kendall, Richard;Patel, Vinod F.;Payton, Marc [Journal of Medicinal Chemistry,2015,vol. 58,# 13,p. 5189 - 5207]

870221-50-4
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50-01-1 Synthesis

50-01-1
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$5.00/25g

870221-49-1
16 suppliers
$140.00/250mg

References