4-(2-Chloropyridin-3-yl)pyriMidine synthesis
- Product Name:4-(2-Chloropyridin-3-yl)pyriMidine
- CAS Number:870221-17-3
- Molecular formula:C9H6ClN3
- Molecular Weight:191.62
166196-84-5
11 suppliers
$338.00/1g
3473-63-0
484 suppliers
$5.00/25g
870221-17-3
12 suppliers
$400.00/500mg
Yield:870221-17-3 83%
Reaction Conditions:
Stage #1: formamidine acetic acidwith sodium methylate in methanol; for 0.166667 h;
Stage #2: 1-(2-chloropyridin-3-yl)-3-dimethylaminopropenone in methanol at 40 - 48;
References:
Hodous, Brian L.;Geuns-Meyer, Stephanie D.;Hughes, Paul E.;Albrecht, Brian K.;Bellon, Steve;Bready, James;Caenepeel, Sean;Cee, Victor J.;Chaffee, Stuart C.;Coxon, Angela;Emery, Maurice;Fretland, Jenne;Gallant, Paul;Gu, Yan;Hoffman, Doug;Johnson, Rebecca E.;Kendall, Richard;Kim, Joseph L.;Long, Alexander M.;Morrison, Michael;Olivieri, Philip R.;Patel, Vinod F.;Polverino, Anthony;Rose, Paul;Tempest, Paul;Wang, Ling;Whittington, Douglas A.;Zhao, Huilin [Journal of Medicinal Chemistry,2007,vol. 50,# 4,p. 611 - 626]
55676-21-6
238 suppliers
$6.00/1g
870221-17-3
12 suppliers
$400.00/500mg