4-(2-METHOXYETHOXY)PIPERIDINE synthesis

6synthesis methods

Product Name:4-(2-METHOXYETHOXY)PIPERIDINE
CAS Number:70978-88-0
Molecular formula:C8H17NO2
Molecular Weight:159.23

tert-butyl 4-(2-methoxyethoxy)piperidin-1-carboxylate

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70978-88-0
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Yield:70978-88-0 93%

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane at 20; for 1 h;

Steps:

11.11B Example 11B: 4- (2-methoxyethoxy) piperidine

To Example 11A (500 mg, 1.93 mmol) was added hydrochloric acid / dioxane (4M, 2 mL) solution, and the mixture was stirred at room temperature for 1 hour. The reaction solution was concentrated and then pumped to dryness to obtain the title compound (288 mg, 93%) as a yellow solid.

References:

CN110938059,2020,A Location in patent:Paragraph 0223-0224; 0228-0230

4045-22-1 Synthesis