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4-(2-METHOXYPHENYL)-4-OXOBUTYRONITRILE synthesis

5synthesis methods
579-74-8 Synthesis
2'-Methoxyacetophenone

579-74-8
243 suppliers
$6.00/1g

4-(2-METHOXYPHENYL)-4-OXOBUTYRONITRILE

113522-19-3
17 suppliers
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: p-toluenesulfonic acid / Ambient temperature
2: 19 percent / CHCl3 / 0.33 h / 0 °C

References:

Ben-David, Iris;Mishani, Eyal;Rozen, Shlomo [Journal of Organic Chemistry,1998,vol. 63,# 14,p. 4632 - 4635]