4,4'-(9H-carbazole-3,6-diyl)dibenzoic acid synthesis

Yield:1258419-79-2 93%

Reaction Conditions:

Stage #1: 4,4’-(9H-carbazole-3,6-diyl)dibenzoic acid dimethyl esterwith sodium hydroxide in tetrahydrofuran;methanol;lithium hydroxide monohydrate; for 24 h;Reflux;
Stage #2: with hydrogenchloride in tetrahydrofuran;methanol;lithium hydroxide monohydrate;

References:

Li, Jian-Rong;Yakovenko, Andrey A.;Lu, Weigang;Timmons, Daren J.;Zhuang, Wenjuan;Yuan, Daqiang;Zhou, Hong-Cai [Journal of the American Chemical Society,2010,vol. 132,# 49,p. 17599 - 17610] Location in patent:supporting information; experimental part