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ChemicalBook CAS DataBase List 4-(4-BROMO-2,6-DIFLUOROBENZYL)MORPHOLINE
1092563-36-4

4-(4-BROMO-2,6-DIFLUOROBENZYL)MORPHOLINE synthesis

2synthesis methods
110-91-8 Synthesis
Morpholine

110-91-8
701 suppliers
$9.00/1g

537013-51-7 Synthesis
4-Bromo-2,6-difluorobenzaldehyde

537013-51-7
233 suppliers
$10.00/1g

4-(4-BROMO-2,6-DIFLUOROBENZYL)MORPHOLINE

1092563-36-4
14 suppliers
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Yield:1092563-36-4 98%

Reaction Conditions:

with sodium tris(acetoxy)borohydride;acetic acid in 1,2-dichloro-ethane at 20; for 18 h;

References:

Sampson, Peter B.;Liu, Yong;Patel, Narendra Kumar;Feher, Miklos;Forrest, Bryan;Li, Sze-Wan;Edwards, Louise;Laufer, Radoslaw;Lang, Yunhui;Ban, Fuqiang;Awrey, Donald E.;Mao, Guodong;Plotnikova, Olga;Leung, Genie;Hodgson, Richard;Mason, Jacqueline;Wei, Xin;Kiarash, Reza;Green, Erin;Qiu, Wei;Chirgadze, Nickolay Y.;Mak, Tak W.;Pan, Guohua;Pauls, Henry W. [Journal of Medicinal Chemistry,2015,vol. 58,# 1,p. 130 - 146] Location in patent:supporting information