4-(4-Fluoro-benzyloxy)-benzonitrile synthesis
3synthesis methods
- Product Name:4-(4-Fluoro-benzyloxy)-benzonitrile
- CAS Number:56442-14-9
- Molecular formula:C14H10FNO
- Molecular Weight:227.23
Yield:56442-14-9 98%
Reaction Conditions:
with F-DEAD-2;bis-phenyl-[4-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phenyl]phosphine in tetrahydrofuran at 20; for 3 h;Mitsunobu reaction;
References:
Dandapani, Sivaraman;Curran, Dennis P. [Journal of Organic Chemistry,2004,vol. 69,# 25,p. 8751 - 8757]