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ChemicalBook CAS DataBase List 4-(4-FLUOROPHENOXY)-2-METHYLANILINE

4-(4-FLUOROPHENOXY)-2-METHYLANILINE synthesis

3synthesis methods
-

Yield:946786-20-5 99%

Reaction Conditions:

with palladium on activated charcoal;hydrogen in ethyl acetate at 20;

Steps:

19.19co

To the solution of B (16 g) in EtOAc (200 ml) was added Pd/C (2 g). The reaction mixture was stirred at room temperature under H2 overnight and filtrated, and the solvent was evaporated to obtained compound C (13 g; 99%). LC-MS: 218 (M+H)+.

References:

US2015/291629,2015,A1 Location in patent:Paragraph 0929