ChemicalBook CAS DataBase List 4-(4-METHOXYPHENOXY)BENZOIC ACID 97

4-(4-METHOXYPHENOXY)BENZOIC ACID 97 synthesis

14synthesis methods

Product Name:4-(4-METHOXYPHENOXY)BENZOIC ACID 97
CAS Number:3525-22-2
Molecular formula:C14H12O4
Molecular Weight:244.24

Benzoic acid, 4-(4-methoxyphenoxy)-, ethyl ester

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3525-22-2
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Yield:3525-22-2 94%

Reaction Conditions:

with water;sodium hydroxide in ethanol at 70; for 3 h;

Steps:

1.D-3.2 The synthesis of DI-7

PI - 6 (0.09 g, 0.33 mmol) was added NaOH (0.13 g, 3.30 mmol) in EtOH/H₂0 (10: 1) solution. The mixture was heated to reflux for 3 h. The mixture was cooled to room temperature and evaporated. The mixture was dissolved in water and slowly acidified with 10% aq. HC1 and extracted with CH₂CI₂. The extract was dried over MgS0₄, filtered, and concentrated to afford PI - 7 (0.08 g, 94%) as white solid.

References:

WO2015/158908,2015,A1 Location in patent:Page/Page column 91