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ChemicalBook CAS DataBase List 4-(4-methylphenoxymethyl)benzoic acid

4-(4-methylphenoxymethyl)benzoic acid synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / acetone / 48 h / Reflux; Inert atmosphere
2: potassium hydroxide / tetrahydrofuran; water / Inert atmosphere

References:

Manos-Turvey, Alexandra;Watson, Emma E.;Sykes, Melissa L.;Jones, Amy J.;Baell, Jonathan B.;Kaiser, Marcel;Avery, Vicky M.;Payne, Richard J. [MedChemComm,2015,vol. 6,# 3,p. 403 - 406]