4-(5-chloropyridin-3-yl)Morpholine synthesis
1synthesis methods
- Product Name:4-(5-chloropyridin-3-yl)Morpholine
- CAS Number:330682-25-2
- Molecular formula:C9H11ClN2O
- Molecular Weight:198.65
Yield:330682-25-2 90%
Reaction Conditions:
with dichloro[4,5-bis(diphenylphosphino)-9,9’-dimethylxanthene]palladium(II);sodium t-butanolate at 75;Inert atmosphere;Buchwald-Hartwig Coupling;
References:
Bourriquen, Florian;Bruneau-Voisine, Antoine;Jeandin, Aliénor;Stihle, Etienne;Fantasia, Serena [Chemistry - A European Journal,2019,vol. 25,# 38,p. 9006 - 9011] Location in patent:supporting information