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4,5-DICHLORO-1H-PYRROLE-2-CARBOXYLIC ACID synthesis

11synthesis methods
4,5-dichloro-N-methoxy-N-methyl-1H-pyrrole-2-carboxamide

1448592-72-0
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Yield:39209-94-4 96%

Reaction Conditions:

with lithium hydroxide in 1,4-dioxane;water; for 12 h;Reflux;

References:

Mahajan, Jyoti P.;Mhaske, Santosh B. [Organic Letters,2017,vol. 19,# 10,p. 2774 - 2776] Location in patent:supporting information