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ChemicalBook CAS DataBase List 4,6-Pyrimidinediamine, 5-nitroso- (9CI)
61908-15-4

4,6-Pyrimidinediamine, 5-nitroso- (9CI) synthesis

2synthesis methods
2434-56-2 Synthesis
4,6-Diaminopyrimidine

2434-56-2
210 suppliers
$25.00/1g

4,6-Pyrimidinediamine, 5-nitroso- (9CI)

61908-15-4
9 suppliers
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Yield: 85%

Reaction Conditions:

with hydrogenchloride;sodium nitrite in water at -10; for 1.5 h;

Steps:

3.4 Synthesis of 4,6-diamino-5-nitrosylpyrimidine
The hydrochloric acid reaction solution was diluted to 1.5 mol / L,Cooled to -10 ° C,Add 82g in batchesSodium nitrite,After stirring for 1.5 h, sodium carbonate was added and the reaction solution was neutralized to pH neutral,Filtered to give a damp 4,6-diamino-5-nitrosylpyrimidine cake.The yield was 85%.

References:

Zhejiang University of Technology;Li, Yongshu;Yan, Yiyi;Chen, Liqi;Mao, Liping;Wang, Yunlong CN103709164, 2016, B Location in patent:Paragraph 0034; 0092; 0105; 0109