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ChemicalBook CAS DataBase List 4-ACETAMIDOBENZENESULFINIC ACID SODIUM SALT
15898-43-8

4-ACETAMIDOBENZENESULFINIC ACID SODIUM SALT synthesis

4synthesis methods
-

Yield: 80%

Reaction Conditions:

with aluminum (III) chloride;1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate;sodium hydrogencarbonate in water;1,2-dichloro-ethane at 20 - 40;

Steps:

2 Example 2: Preparation of sodium 4-acetamidobenzenesulfinate
Under normal pressure, to a 100 mL three-necked flask with mechanical agitation,20 mL of 1,2-dichloroethane, 3.0 mmol was added successively at 20 ° CN-acetylAniline, 24.0 mmol of aluminum trichloride, 3.0 mmol of the above-mentioned self-made DABSO, and then heated to 25-40 ° C for 20-24 h. When the content of N-acetanilide in the reaction solution was less than 1% by liquid chromatography End. The post-treatment was carried out in the same manner as in Example 1 to give 0.53 g of a white solid powder of sodium 4-acetamidobenzenesulfinate in 80% yield.

References:

Tianjin University;Zhang Xubin;Wang Tianlei;Wu Botao;Wang Fumin;Ni Ruwei;Ni Hao CN107098834, 2017, A Location in patent:Paragraph 0031; 0033; 0034; 0035; 0036

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