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4-(AZEPANE-1-SULFONYL)-BENZOIC ACID synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: triethylamine / dichloromethane / 5 h / 20 °C / Inert atmosphere; Cooling with ice
2: lithium hydroxide monohydrate / methanol; water / 2 h / 20 °C

References:

Qin, Rongfei;Wang, Pengxu;Wang, Bin;Fu, Lei;Batt, Sarah M.;Besra, Gurdyal S.;Wu, Chengwei;Wang, Yanan;Huang, Haihong;Lu, Yu;Li, Gang [European Journal of Medicinal Chemistry,2022,vol. 231,art. no. 114145]

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