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ChemicalBook CAS DataBase List 4-Benzyloxy-3-chloro-phenol

4-Benzyloxy-3-chloro-phenol synthesis

2synthesis methods
-

Yield:86902-27-4 87%

Reaction Conditions:

Stage #1: 4-benzyloxy-3-chlorobenzaldehydewith 3-chloro-benzenecarboperoxoic acid in dichloromethane at 20; for 120 h;
Stage #2: with sodium hydroxide in methanol; for 1 h;Further stages.;

References:

Potashman, Michele H.;Bready, James;Coxon, Angela;Demelfi Jr., Thomas M.;DiPietro, Lucian;Doerr, Nicholas;Elbaum, Daniel;Estrada, Juan;Gallant, Paul;Germain, Julie;Gu, Yan;Harmange, Jean-Christophe;Kaufman, Stephen A.;Kendall, Rick;Kim, Joseph L.;Kumar, Gondi N.;Long, Alexander M.;Neervannan, Seshadri;Patel, Vinod F.;Polverino, Anthony;Rose, Paul;Van Der Plas, Simon;Whittington, Douglas;Zanon, Roger;Zhao, Huilin [Journal of Medicinal Chemistry,2007,vol. 50,# 18,p. 4351 - 4373]