4-BROMO-N-CYCLOPROPYL-2-METHYL-BENZAMIDE(WXG00232) synthesis
- Product Name:4-BROMO-N-CYCLOPROPYL-2-METHYL-BENZAMIDE(WXG00232)
- CAS Number:345965-99-3
- Molecular formula:C11H12BrNO
- Molecular Weight:254.12
68837-59-2
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765-30-0
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345965-99-3
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Yield:345965-99-3 99%
Reaction Conditions:
Stage #1: 4-bromo-2-methylbenzoic acidwith oxalyl dichloride;N,N-dimethyl-formamide in dichloromethane at 20; for 16 h;
Stage #2: Cyclopropylaminewith triethylamine in dichloromethane at 0 - 20; for 2.25 h;
References:
Liu, Yong;Laufer, Radoslaw;Patel, Narendra Kumar;Ng, Grace;Sampson, Peter B.;Li, Sze-Wan;Lang, Yunhui;Feher, Miklos;Brokx, Richard;Beletskaya, Irina;Hodgson, Richard;Plotnikova, Olga;Awrey, Donald E.;Qiu, Wei;Chirgadze, Nickolay Y.;Mason, Jacqueline M.;Wei, Xin;Lin, Dan Chi-Chia;Che, Yi;Kiarash, Reza;Fletcher, Graham C.;Mak, Tak W.;Bray, Mark R.;Pauls, Henry W. [ACS Medicinal Chemistry Letters,2016,vol. 7,# 7,p. 671 - 675] Location in patent:supporting information
68837-59-2
337 suppliers
$5.00/1g
345965-99-3
12 suppliers
inquiry