4-Butoxy-1,1,1-trofluoro-3-buten-2-one synthesis
- Product Name:4-Butoxy-1,1,1-trofluoro-3-buten-2-one
- CAS Number:120407-73-0
- Molecular formula:C8H11F3O2
- Molecular Weight:196.17
111-34-2
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407-25-0
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120407-73-0
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Yield: 79%
Reaction Conditions:
with pyridine in chloroform at 5 - 20; for 15 h;
Steps:
1.1
1.1) 4-Butoxy-1,1,1-trifluorobut-3-en-2-one With stirring at 5° C., 79.9 g (0.38 mol) of trifluoroacetic anhydride-dissolved in 100 ml of trichloromethane-were added to a mixture of 29.9 g (0.38 mol) of pyridine and 50.0 g (0.38 mol) of butyl vinyl ether in 200 ml of trichloromethane. After the addition, stirring was continued at room temperature for another 15 h. 300 ml of water were then added to the mixture, and the organic phase was separated off, dried and concentrated. This gave 59 g (79% of theory) of a yellowish oil. 1H-NMR: [CDCl3] 0.96 (t, 3H); 1.41 (m, 2H); 1.73 (m, 2H); 4.04 (t, 2H); 5.85 (d, 1H); 7.90 (d, 1H)
References:
Rosinger, Christopher;Ziemer, Frank;Auler, Thomas;Bickers, Udo;Hacker, Erwin US2008/269052, 2008, A1 Location in patent:Page/Page column 24-25
111-34-2
243 suppliers
$13.00/25mL
1522-22-1
273 suppliers
$6.00/1g
120407-73-0
25 suppliers
$118.00/500mg
109-92-2
267 suppliers
$16.00/25mL
407-25-0
438 suppliers
$9.00/1g
120407-73-0
25 suppliers
$118.00/500mg