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ChemicalBook CAS DataBase List 4-chloro-2-(1-Methyl-1H-pyrazol-5-yl)phenol

4-chloro-2-(1-Methyl-1H-pyrazol-5-yl)phenol synthesis

2synthesis methods
-

Yield:36141-23-8 55% ,36141-22-7 27%

Reaction Conditions:

with acetic acid in ethanol; for 18 h;Reflux;

References:

Swain, Nigel. A.;Batchelor, Dave;Beaudoin, Serge;Bechle, Bruce M.;Bradley, Paul A.;Brown, Alan D.;Brown, Bruce;Butcher, Ken J.;Butt, Richard P.;Chapman, Mark L.;Denton, Stephen;Ellis, David;Galan, Sebastien R. G.;Gaulier, Steven M.;Greener, Ben S.;De Groot, Marcel J.;Glossop, Mel S.;Gurrell, Ian K.;Hannam, Jo;Johnson, Matthew S.;Lin, Zhixin;Markworth, Christopher J.;Marron, Brian E.;Millan, David S.;Nakagawa, Shoko;Pike, Andy;Printzenhoff, David;Rawson, David J.;Ransley, Sarah J.;Reister, Steven M.;Sasaki, Kosuke;Storer, R. Ian;Stupple, Paul A.;West, Christopher W. [Journal of Medicinal Chemistry,2017,vol. 60,# 16,p. 7029 - 7042] Location in patent:supporting information