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ChemicalBook CAS DataBase List 4-chloro-2-[4-(trifluoromethyl)phenyl]quinazoline
1041568-57-3

4-chloro-2-[4-(trifluoromethyl)phenyl]quinazoline synthesis

3synthesis methods
2-[4-(Trifluoromethyl)phenyl]quinazolin-4(3H)-one

83800-83-3
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4-chloro-2-[4-(trifluoromethyl)phenyl]quinazoline

1041568-57-3
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Yield:1041568-57-3 86%

Reaction Conditions:

with N,N-diethylaniline;trichlorophosphate in benzene;Reflux;

References:

Maxwell, Aoife C.;Flanagan, Susan P.;Goddard, Richard;Guiry, Patrick J. [Tetrahedron Asymmetry,2010,vol. 21,# 11-12,p. 1458 - 1473] Location in patent:experimental part