4-(CHLOROMETHYL)BENZYL ALCOHOL 99 synthesis
- Product Name:4-(CHLOROMETHYL)BENZYL ALCOHOL 99
- CAS Number:16473-35-1
- Molecular formula:C8H9ClO
- Molecular Weight:156.61
1642-81-5
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$17.00/5g
16473-35-1
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$16.00/250mg
Yield: 96%
Reaction Conditions:
with borane-THF in tetrahydrofuran at 20;
Steps:
1.1 Example 1; (1) 4-CHLOROMETHYLBENZYL Alcohol
Example 1: (1) [4-CHLOROMETHYLBENZYL] Alcohol To a solution of 4-chloro-4-toluic acid in tetrahydrofuran (THF, 60 [ML)] was added 1 M borane THF solution (90 [ML).] The mixture was stirred at room temperature overnight and quenched by addition of methanol (50 ml). The solvent was evaporated off and the residue was purified by silica gel column chromatography (hexane/ethyl acetate = 4/1 to 3/1) to obtain 4-chloromethylbenzyl Alcohol (8.84 g, 96%) as a colorless solid.
References:
BAYER HEALTHCARE AG WO2003/106403, 2003, A1 Location in patent:Page 23
589-29-7
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$5.00/5g
16473-35-1
121 suppliers
$16.00/250mg
876-08-4
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$11.00/25g
16473-35-1
121 suppliers
$16.00/250mg
34040-64-7
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$16.00/1g
16473-35-1
121 suppliers
$16.00/250mg